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Challenge in protein-small molecule Interactions
https://nakamura-u.repo.nii.ac.jp/records/240
https://nakamura-u.repo.nii.ac.jp/records/240ad057f7a-37bb-45ae-aa76-bd74a113e471
名前 / ファイル | ライセンス | アクション |
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01-003-03-01- Challenge in protein-small・・・内山 (295.4 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2010-04-05 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Challenge in protein-small molecule Interactions | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | conformational change | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | torsion strain | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | protein-protein interaction | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | protein binding surface areas | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | tumor necrosis factor | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | TNFR | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
内山, 文昭
× 内山, 文昭 |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | (Abstract) The potential for driving force in protein-ligand binding are discussed in this review. The conformational change in protein-ligand interaction is dependent on characteristics of proteins. Proteins which do not change conformation before ligand binding compose of constraint binding site residues. The conformation of ligand-binding sites of these proteins adopts disallowed Ramachandran angels. Conformational changes in protein-ligand binding result to adopt energetically unfavorable or disallowed Ramachandran angels. These findings show that an element of driving forces in protein-ligand binding may be the generation of torsion-angle strain. |
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書誌情報 |
中村学園大学薬膳科学研究所研究紀要 en : Proceedings of PAMD Institute of Nakamura Gakuen University 号 3, p. 1-6, 発行日 2010-04-05 |
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出版者 | ||||||
出版者 | 中村学園大学薬膳科学研究所 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18829384 |