@article{oai:nakamura-u.repo.nii.ac.jp:00000240,
 author = {内山, 文昭},
 issue = {3},
 journal = {中村学園大学薬膳科学研究所研究紀要, Proceedings of PAMD Institute of Nakamura Gakuen University},
 month = {Apr},
 note = {(Abstract)
The potential for driving force in protein-ligand binding are discussed in this review. The conformational change in protein-ligand interaction is dependent on characteristics of proteins. Proteins which do not change conformation before ligand binding compose of constraint binding site residues. The conformation of ligand-binding sites of these proteins adopts disallowed Ramachandran angels. Conformational changes in protein-ligand binding result to adopt energetically unfavorable or disallowed Ramachandran angels. These findings show that an element of driving forces in protein-ligand binding may be the generation of torsion-angle strain.},
 pages = {1--6},
 title = {Challenge in protein-small molecule Interactions},
 year = {2010},
 yomi = {ウチヤマ, フミアキ}
}