{"created":"2023-06-19T09:16:53.655079+00:00","id":259,"links":{},"metadata":{"_buckets":{"deposit":"f489b1bf-e062-4d19-9cfc-b0b033abc1ea"},"_deposit":{"created_by":17,"id":"259","owners":[17],"pid":{"revision_id":0,"type":"depid","value":"259"},"status":"published"},"_oai":{"id":"oai:nakamura-u.repo.nii.ac.jp:00000259","sets":["27","27:39"]},"author_link":["245"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2009-04-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"24","bibliographicPageStart":"9","bibliographic_titles":[{"bibliographic_title":"中村学園大学薬膳科学研究所研究紀要"},{"bibliographic_title":"Proceedings of PAMD Institute of Nakamura Gakuen University","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"(Abstract)\nMetabolic phenotypes are the products of interactions among a variety of factors-dietary,otherlifestyle/environmental,gut microbial and genetic.We focus on the description of the state of the art proteomic/metabolomic platforms using human\nurine established. In this review the current situation of clinicalproteomics and metabo1omics needed to discover new human urine analysis is pre-sented.The data in the current literature indicate that although a thorough investigation of the entire urinary analysis is still a distant goal,technical applications are already available.In the future,metabolic phenotyping applied to urine analytical data offers the potential to develop an area of aetiopathogenetic knowledge.\n","subitem_description_type":"Abstract"}]},"item_10002_description_6":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"(緒言)\n生体では, 誕生から死にいたるまで絶え間なく尿が生産され, 健常人では1日に約1.5リットルの尿を排泄しており人生80年の間に出す尿の平均量は約35トンといわれている。尿成分は,約98%が水分,約2%が尿素,その他, タンパク質,糖,赤血球およびヘモグロビン, ケトン体,  ビリルビンおよびウロビリノーゲン, 亜硝酸塩, ポルフィリン体,バニリルマンデル酸等の有機成分,食塩,ナトリウム,カリウム,カルシウム,マグネシウム, 塩素,総硫酸,エーテル硫酸,  リン,鉄等の無機成分から構成されている。 これらの組成は,血清成分に比べ著しく変動しやすく, 尿成分の定性・定量解析することで書疾患,肝疾患,糖尿病,先天性代謝異常,退行性疾患, 感染症,代謝異常,栄養障害の診断および治療モニタリングがなされており,  さらに新たな疾患関連物質のバイオマーカ一探索が期待されている。本稿では, 尿についての -般的所見, 検査方法・疾患から最先端技術をもちいたヒト尿プロテオーム解析・メタボローム解析について概説する。","subitem_description_type":"Other"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"中村学園大学薬膳科学研究所"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"18829384","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"治京, 玉記"},{"creatorName":"ジキョウ, タマキ","creatorNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"245","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2013-09-30"}],"displaytype":"detail","filename":"01‐003‐02‐02‐プロテオミクス・・・ 治京.pdf","filesize":[{"value":"3.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"01‐003‐02‐02‐プロテオミクス・・・ 治京","url":"https://nakamura-u.repo.nii.ac.jp/record/259/files/01‐003‐02‐02‐プロテオミクス・・・ 治京.pdf"},"version_id":"088a19c1-961b-4d83-9aea-095663365158"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"尿解析","subitem_subject_scheme":"Other"},{"subitem_subject":"プロテオーム解析","subitem_subject_scheme":"Other"},{"subitem_subject":"メタボローム解析","subitem_subject_scheme":"Other"},{"subitem_subject":"プロテオーム","subitem_subject_scheme":"Other"},{"subitem_subject":"メタボローム","subitem_subject_scheme":"Other"},{"subitem_subject":"プロテオミクス","subitem_subject_scheme":"Other"},{"subitem_subject":"メタボロミクス","subitem_subject_scheme":"Other"},{"subitem_subject":"ヒト尿解析","subitem_subject_scheme":"Other"},{"subitem_subject":"urinary analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"proteomic analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"metabolomic analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"プロテオミクスおよびメタボロミクスによるヒト尿解析","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"プロテオミクスおよびメタボロミクスによるヒト尿解析"},{"subitem_title":"Human Urine Analysis Using Proteomics and Metabolomics","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"17","path":["27","39"],"pubdate":{"attribute_name":"公開日","attribute_value":"2009-04-10"},"publish_date":"2009-04-10","publish_status":"0","recid":"259","relation_version_is_last":true,"title":["プロテオミクスおよびメタボロミクスによるヒト尿解析"],"weko_creator_id":"17","weko_shared_id":-1},"updated":"2023-06-19T10:17:36.637480+00:00"}