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Peptide Phage Display
https://nakamura-u.repo.nii.ac.jp/records/268
https://nakamura-u.repo.nii.ac.jp/records/26843cf7c5c-4156-4132-9ddb-861c3fdb2eeb
名前 / ファイル | ライセンス | アクション |
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01‐003‐01‐02‐ Peptide Pharge Display・・・内山、毛利、千原 (375.0 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-03-31 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Peptide Phage Display | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | phage display | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | disulfidebridge | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | constraint | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | conformational diversity | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
主題 | random peptides | |||||
キーワード | ||||||
言語 | en | |||||
主題Scheme | Other | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Uchiyama, Fumiaki
× Uchiyama, Fumiaki× Mouri, Saeko× Chihara, Tomomi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | (Abstract) Phage display is emerging as a promising strategy for the discovery of peptide ligands that are used for analytical tools, drug discovery, and target validations. Phage display technology can produce a huge number of peptides and generate novel peptide ligands. Phage display technology has successfully managed to create some peptide ligand. The structural analysis of ligands shows that the conformational desigh of peptides in library is important for structural relationship among peptides on phage, synthetic peptides and non-peptidic compounds as well as for selecting high-affinity ligands that bind to every target from a phage peptide library. Key issues concern constraints on the conformation of peptides on the phage and the development of chemically synthesized peptides derived from peptides on pharge. This review dis-cusses studies related to the conformation of peptides selected from phage display peptide libraries in addition to the conversion from peptides to non-peptides. |
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書誌情報 |
中村学園大学薬膳科学研究所研究紀要 en : Proceedings of PAMD Institute of Nakamura Gakuen University 号 1, p. 11-22, 発行日 2008-03-31 |
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出版者 | ||||||
出版者 | 中村学園大学薬膳科学研究所 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18829384 |